DO inhibitor
VX-11e Compound StructureNLG919Find Out More>>
NLG919 is really a effective IDO (indoleamine-(2,3)-dioxygenase) pathway inhibitor with Ki/EC50 of 7 nM/75 nM in cellular-free of charge assays. Stage 1.
Associated Products: Indoximod, INCB024360 analogue
TNF-α inhibitor
Trovirdine (LY-300046) Compound ConstructionCPI-1189Get More Information>>
CPI-1189(REN-1189) is really a TNF-α discharge inhibitor potentially for the treatment of sciatica and postherpetic neuralgia.
Connected Goods: CX691 , Substance 4
Antiepileptic Medicine
DB07268 Compound StructureValrocemideLearn More>>
Valrocemide(Tv set-1901), is surely an antiepileptic medication (AED). Valrocemide carries a large spectrum of anticonvulsant activity and promising probable like a new AED.
Related Products: Lvguidingan , NS 638
VEGFR Inhibitor
BML-210 Substance ConstructionSU 5205Find Out More>>
SU 5205 is actually a VEGFR2 inhibitor.
Related Goods: PF-CBP1 , SR-3029
PDGFR Inhibitor
AMG-337 Chemical substance ConstructionNSC 86429Discover More>>
SU-4312, often known as DMBI, can be a potent and particular inhibitor of VEGFR and PDGFR tyrosine kinases (IC50 principles are .8 and 19.4 μM respectively). SU4312 unexpectedly guards against MPP(+) -stimulated neurotoxicity via picky and straight inhibition of neuronal NOS.
Relevant Merchandise: I-CBP112 , GK921
IKr Channel Blocker
JNJ-42165279 Chemical substance FrameworkCK-1752Find Out More>>
Sematilide, also known as CK-1752, can be a type III antiarrhythmic. This is a particular postponed rectifier K+ present (IKr) route blocker. It inhibits rapidly activating Ik in guinea pig atrial myocytes, leading to the prolongation of measures possible timeframe and refractoriness.
Associated Items: XL-652 , WAY 200070