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Hot Materials in Protease Inhibitor Catalogue

proteasome

MG-132  CAS No. 133407-82-6

MG-132  is undoubtedly an inhibitor of proteasome with IC50 of 100 nM within a mobile-cost-free assay, and in addition inhibits calpain with IC50 of 1.2 μM.

20S proteasome

Bortezomib CAS No. 179324-69-7

Bortezomib (PS-341) can be a powerful 20S proteasome inhibitor with Ki of .6 nM inside the mobile phone-free of cost assay.

proteasome

Carfilzomib CAS No. 868540-17-4

Carfilzomib (PR-171) is undoubtedly an long lasting proteasome inhibitor with IC50 of <5 nM in ANBL-6 muscle, showcased preferential in vitro inhibitory durability from the ChT-L exercising in the β5 subunit, but basically no final result on the PGPH and T-L measures.

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