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Several-kinase Inhibitor

Flumatinib

Flumatinib is really a multiple-kinase inhibitor with IC50 Rules of 1.2 nM, 307.6 nM and 2662 nM for c-Abl, PDGFRβ and c-Set correspondingly.

Relevant Merchandise: EP Z020411 2HCl

FAAH Inhibitor

BPF-04457845

BPF-04457845 could be a highly efficacious and critical FAAH inhibitor with IC50 guidelines is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, correspondingly.

Relevant Merchandise: LTI-291,Donepezil

SIRT6 Inhibitor

OSS128167

OSS_128167 is a certain SIRT6 inhibitor with IC50 values of 89, 1578 and 751 μM for SIRT6, SIRT1 and SIRT2, correspondingly.

Pertinent Items: Quinine dihydrochloride

CRF1 Receptor Antagonist

CP 376395

CP 376395 is really a efficient and discerning Corticotropin discharging factor 1 (CRF1) receptor antagonist.

Attached Products: GNE-617 , OSS128167

TMEM16A Inhibitor

CaCCinh-A01

CaCCinh-A01 is surely an inhibitor of both TMEM16A and calcium supplement-induced chloride course (CaCC) with IC50s of 2.1 and 10 μM, correspondingly.

Connected Items: IPTG ,GNE-617

Products Catalog

Element Neighborhood library

45 forms of chemical libraries for best throughput tests and high content screening.

Investigation Regions

Proteases/Proteasome

Chromatin/Epigenetic

JAK/STAT signaling

Tyrosine Kinase/Adaptors

PI3K/Akt/mTOR Signaling

MAPK Signaling

Apotosis

Ubiquitination

Angiogenesis

Immunology/Pain

DNA Troubles/DNA Renovation

See Significantly more…

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