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Well-appreciated Components in Epigenetics Brochure

Histone Methyltransferase

EPZ004777

CAS No. 1338466-77-5

EPZ004777 can be quite a potent, critical DOT1L inhibitor with IC50 of .4 nM inside a cellphone-cost-free of charge assay.

Epigenetic Viewers Internet site cope with

I-BET151

CAS No. 1300031-49-5

I-BET151 (GSK1210151A) is unquestionably a remarkable particular Visualize inhibitor for BRD2, BRD3 and BRD4 with IC50 of .5 μM, .25 μM, and .79 μM in mobile cell phone-costs-cost-free assays, respectively.

DNA Methyltransferase

SGI-1027

CAS No. 1020149-73-8

SGI-1027 is really a effective and certain inhibitor of DNA methyltransferase (DNMT) with IC50 of 6, 8, 7.5 μM for DNMT1, DNMT3A, and DNMT3B, respectively.

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